Neurotransmitter forstyrrelserne man ser i ADHD fænomenet kan være relateret til b6 vitamin mangel – mange af de neurtransmittere der er forstyrrelser i ved ADHD fænomenet er alle afhængige af b6 som coenzym ved deres syntese.
“Since dopamine, noradrenalin, serotonin, glutamate, GABA are formed or metabolized by PLP-dependent enzymes (Fig. 1), it is reasonable to assume that biochemical disturbances revealed in ADHD (serotonin and catecholamine deficiency, glutamate/GABA imbalance and plasma TRP excess) are of pyridoxine-dependent origin”
Selvom jeg savner fuld adgang til artiklen så påstår den her forskergruppe at deres data fortæller dem at b6 tilskud kan normalisere alle ADHD symptomer i løbet af et par år.
“According to our data, multi-year pyridoxine treatment normalizes completely the pattern of ADHD behavior, without causing any serious side effects.”
Et interessant lille studie med magnesium og b6 givet sammen peger også i retning af signifikante forbedringer. Og ved ophør af b6-magnesium tilskud skete der en tilbagefald af symptomer.
“In almost all cases of ADHD, Mg-B6 regimen for at least two months significantly modified the clinical symptoms of the disease: namely, hyperactivity and hyperemotivity/aggressiveness were reduced, school attention was improved. In parallel, the Mg-B6 regimen led to a significant increase in Erc-Mg values. When the Mg-B6 treatment was stopped, clinical symptoms of the disease reappeared in few weeks together with a decrease in Erc-Mg values. This study brings additional information about the therapeutic role of a Mg-B6 regimen in children with ADHD symptoms.”
https://pubmed.ncbi.nlm.nih.gov/16846100/
Voksne med ADHD har også mangel af flere b-vitaminer – årsagssammenhængen kan selvfølgelig ikke påvises men alligevel er det interessant at de mangler b2, b6 og b9 i højere grad end folk der ikke har diagnosen:
“Lower concentrations of vitamins B2, B6 and B9 were associated with the ADHD diagnosis, and B2 and B6 also with symptom severity. Smokers had lower levels of vitamins B2 and B9.”
Seabridge Bioenergetics 
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