TL;DR: PUFA induces af stress response in the liver that turns on the aryl hydrocarbon receptor AHR.This turns up transctiption of the fat storage programming, which down the line acts to increase transcription of SCD1 and other fat storage/lipogenic enzymes – SCD1 turns Saturated fats to monounsatured fats, and now the metabolic rate slows down … Continue reading Dietary PUFA -driver of the mammalian hibernation state and Human Obesity?